Surgical Antibiotic Prophylaxis in Georgia | ICARS

Optimising use of antibiotics for Surgical Antibiotic Prophylaxis (SAP)

Results

  • Patient safety: The transition to evidence-based single-dose prophylaxis did not increase SSI incidence – alleviating a central barrier to practice change among clinicians.

  • Economic efficiency: Reduction in antibiotic use, nursing labour costs, and SSI resource needs indicate that SAP optimisation is not only clinically beneficial but also cost-saving.

  • Clinical culture change: Frontline surgical teams became increasingly engaged, using run charts and feedback discussions to monitor their own progress and, in several cases, voluntarily expanding training to additional departments.

  • National policy development: The Ministry of Health’s approval of the SAP guideline provided an authoritative standard and set the foundation for future AMS scale-up. The collaboration among the National Centre for Disease Control, the Ministry of Health, ICARS, the WHO Regional Office for Europe, professional associations, and private hospital networks established a governance model that can support broader AMR initiatives nationwide.

  • In partnership with The British Society of Antibiotic Chemotherapy three open access courses have been launched. These courses are available in Georgian and English and will remain available after the completion of the project to support capacity building during the nationwide scale-up phase of the AMS programme.

  • National implementation and evaluation of the SAP guidelines have been included as a priority action in the new AMR National Action Plan.

Context

Antimicrobial resistance (AMR) is a serious threat in Georgia and beyond. While in Georgia, actions to contain the development and spread of AMR have mainly focused on strengthening the surveillance systems and implementing modern methods for infection prevention and control (IPC); no concrete actions have been implemented to establish Antimicrobial Stewardship programmes [ASPs].

Problem

In Georgia, as in many other parts of the world, there is a worrisome inappropriate use of antibiotics for surgical prophylaxis characterised by a high use of broad-spectrum antibiotics and prolonged dosing.

Project overview

The project has been implemented in ten hospitals, targeting the following surgical procedures: herniorrhaphy, hip joint surgery, endoprosthesis, and Caesarean section. The implementation of the ASP is organised across four Work Packages (WPs)

  1. Project management
  2. Systematic implementation of a mixed methods approach, including development of the WHO toolkit for antimicrobial stewardship including:
    • development of context-specific SAP guidelines,
    • education & training of the clinical teams on the guidelines systematic data collection, analysis and reporting of data.
    • implementation of active surveillance of surgical site infections (SSI)
    • implementation of the quality improvement methodology (Plan-Do-Study-Act-Adjust)
  3. Tailored Antimicrobial Resistance Programme (TAP), qualitative methodology to identify the context-specific organisational and behavioural factors that support implementation and scale-up of the ASP.
  4. Economic evaluation.

Intended outcomes

This project aims to foster the appropriate use of antibiotics for Surgical Antibiotic Prophylaxis (SAP) in selected departments of Georgian hospitals by implementing an antimicrobial stewardship programme (ASP). The project aims to achieve 60% SAP guideline compliance within 12 months of launching the ASP. The main outcome measure is percentage of compliance with the four components of the SAP guideline which covers:

  1.  antibiotic choice
  2. dose
  3. timing
  4. duration of prophylaxis

Other outcomes include assessment of the prevalence of surgical site infections (SSI’s) for the selected procedures, and increased understanding of the context-specific organisational, behavioural and economic factors that support implementation and scale-up of the ASP.

This project will strengthen antimicrobial stewardship (AMS) at hospital level in Georgia by facilitating the establishment of a coalition of good practice centers in which key stakeholders such as the MoH, Public Health authorities, clinicians, managers of the hospitals, WHO-EURO and ICARS can demonstrate the relevance and sustainability of implementing AMS programmes within the Georgian context.

Gloria Cristina Cordoba Currea, AMR Advisor, ICARS