We are looking for low- and middle-income countries (LMICs) committed to mitigating antimicrobial resistance and willing to show leadership by developing a demonstration project in partnership with ICARS. Through such a project, your country will receive support in identifying and implementing a solution to a specific antimicrobial resistance challenge that your country seeks to solve. Doing so, you will contribute to the development of the ICARS concept and to ensure that ICARS responds to the needs of low- and middle-income countries.
Countries requesting support from ICARS are equal partners and collaborators on ICARS projects. To enable active participation now and in the future, when appropriate, financial support is provided to support capacity and capabilities in countries. The countries eligible to receive support are those on the DAC (OECD Development Assistance Committee) list of ODA recipients.
When considering activities and engagement, ICARS will take into account:
- Political, policy and technical engagement at all levels including willingness to uptake and sustain identified value adding solutions
- Evidence from the government that they wish to address antimicrobial resistance through a One Health approach
- Existing human resources and research infrastructure to co-execute the research projects
- Alignment with other global and national initiatives.
Application & co-development process
See below the framework for ICARS’ demonstration projects and the associated guidelines and templates corresponding to each phase of the application process and project development.
Countries interested in co-developing a demonstration project with ICARS should as a first step submit an Expression of Interest (EoI) through their relevant ministries. That same ministry will be responsible for the development and implementation as well as the further uptake of the solutions identified as part of the project, being part of the process every step of the way, with support from ICARS.
Within maximum four weeks of receiving the EoI, ICARS provides written feedback and arranges a feedback meeting.
After approval of the EoI and discussions with ICARS, the Responsible Ministry and ICARS initiate the co-development of the Concept Note, which is a more detailed description of the research project idea.
A Lead Research Institution and a Project Coordinator are assigned to the project by the Responsible Ministry. Other relevant national research institutions/universities and stakeholders should also be involved at this stage.
ICARS’ Executive Management will assess the Concept Note upon submission by the Responsible Ministry.
At this stage, ICARS and the Repsonsible Ministry (or ministries) sign Memorandum of Understanding, expressing their commitment to work together on one or more implementation projects to tackle antimicrobial resistance.
After the Concept Note is approved and the MoU has been signed, the next step is to co-develop a Project Proposal, which is a detailed description of all aspects of the research project.
Following submission by the Responsible Ministry to ICARS, ICARS’ Technical Advisory Forum (TAF) will conduct a scientific evaluation of the proposal.
After receiving feedback from ICARS and the TAF, the Responsible Ministry and partners will revise and submit an amended proposal with advice from ICARS.
If the Project Proposal is approved by ICARS’ Executive Management, it will be presented to the ICARS Steering Committee for final approval and allocation of the grant.
Following the approval of the Project Proposal the next step is for the Responsible Ministry and partners to implement the project with advise from ICARS.
During project implementation the Responsible Ministry and partners must ensure adherence to ICARS’ guidelines and policies. This also entails to enter into a Partnership Agreement within the first half year of the research project.
Here is a selection of the ICARS projects currently being developed in LMICs.
Optimising use of antibiotics for Surgical Antibiotic Prophylaxis (SAP)
Development and implementation of SAP guidelines in hospitals.
Reducing the use of antimicrobials in aquaculture (pangasius)
Investigating the impact and barriers for replacing antibiotics with vaccines.
Tackling the overuse of antibiotics in pig production (colistin)
Reducing the use of colistin in agriculture through alternative interventions.