Decreasing CRE transmission between hospitals, communities & domesticated animals (I-CRECT)

The overall aim is to reduce and evaluate transmission of CRE from discharged patients to household members, community, livestock and the environment. To assess relatedness of isolates in different one health departments, including transmission of colistin resistance from animals to humans. In a cluster randomized controlled trial, the effect of a bundle of interventions will be assessed on CRE transmission from CRE+ index patients discharged from hospital to household members. An information, communication, education and hygiene intervention, developed in collaboration with local health authorities, will aim to improve hygiene and decrease antibiotic use.