This paper maps the current evidence on interventions to reduce antimicrobial resistance (AMR) in Latin America and the Caribbean. Using articles from PubMed, Web of Science, LILACS, and grey literature, the authors focused on reports on the implementation of AMR programmes, interventions, or policies aimed at tackling AMR that were published between January 2018 and December 2024. The findings show that most interventions are concentrated in the human health sector, with a major gap in One Health research integrating animal, environmental, and human health.