Our thematic areas – ICARS

Our thematic areas

Explore our key themes in tackling antimicrobial resistance, from climate change to infection prevention and stewardship.

Thematic portfolio: ICARS’ integrated approach to addressing Antimicrobial Resistance

Antimicrobial resistance (AMR) is one of the defining global health challenges of our time — a complex crisis that transcends borders, species, and ecosystems. ICARS recognises that addressing AMR requires a holistic, interdisciplinary approach grounded in the One Health framework, integrating human health, animal health, and the environment.

ICARS’ thematic portfolio explores the critical dimensions shaping the AMR landscape today, offering insights into the drivers, interventions, and innovations that will help safeguard health for people, animals, and the planet. Each theme highlights key challenges, ongoing research, and impactful projects supported by ICARS in low- and middle-income countries (LMICs).

Climate Change and environmental dimensions of AMR

Climate change and environmental factors are critical but often overlooked drivers of AMR. Rising temperatures and ecosystem changes alter disease patterns and antimicrobial use, while contaminated wastewater and agricultural runoff foster resistance in natural and built environments. Projects focus on sustainable, climate-smart interventions that reduce environmental AMR risks.

Vaccination and immunity strengthening

Vaccines reduce infections and antibiotic demand, limiting the emergence of resistance. Integrating vaccination efforts with AMR strategies in human and animal health can reduce antimicrobial residues in the environment and support healthier, more resilient populations.

Diagnostic and Antimicrobial Stewardship

Timely, accurate diagnosis combined with responsible antibiotic use is vital to preserving treatment effectiveness. Diagnostic and antimicrobial stewardship initiatives improve prescribing practices, strengthen surveillance, and promote sustainable antimicrobial use across One Health sectors.

Infection Prevention and Control (IPC)

Effective IPC reduces infection spread and unnecessary antibiotic use, crucial in healthcare, animal production, and communities. Strengthening IPC through evidence-based practices, diagnostics, and community engagement supports improved health outcomes and helps slow AMR development.

Gender and equity in AMR

Gender and social inequities influence antibiotic use, exposure, and access to resources. Addressing these factors enhances the effectiveness and inclusivity of AMR strategies, ensuring that vulnerable and marginalised groups receive equitable protection and support.

Our global presence expand over 24 countries and territories

Our projects inform policy and practice around the world. ICARS works with Low- and Middle-Income Countries around the world to tackle antimicrobial resistance and support the implementation of their AMR National Action Plans.

Our global presence expand over 24 countries and territories

Our projects inform policy and practice around the world. ICARS works with Low- and Middle-Income Countries around the world to tackle antimicrobial resistance and support the implementation of their AMR National Action Plans.

What out partner says

ICARS Global is dedicated to addressing antimicrobial resistance (AMR) through targeted actions across key areas. From combating the effects of climate change on AMR, to promoting antimicrobial stewardship and infection prevention, we work to implement sustainable solutions.

A Strategic Approach to Combating Antimicrobial Resistance

“Fighting antibiotic resistance comes in small steps that should be strategic, orderly and well thought out. Well within the one health concept, our interventions start on the consumer’s table and ends in the environment. We are confident that with the solution we offer we can have an impact in the fight against antimicrobial resistance.”

Wejdene Mansour | Associate Professor

A Strategic Approach to Combating Antimicrobial Resistance

“Fighting antibiotic resistance comes in small steps that should be strategic, orderly and well thought out. Well within the one health concept, our interventions start on the consumer’s table and ends in the environment. We are confident that with the solution we offer we can have an impact in the fight against antimicrobial resistance.”

Wejdene Mansour | Associate Professor