Antimicrobial Stewardship Impact on Antibiotic Use in Three Tertiary Hospitals in Zambia: A Comparative Point Prevalence Survey
This study looked at how a programme to improve antibiotic use in hospitals (called antimicrobial stewardship, or AMS) affected the way antibiotics were prescribed at three hospitals in Zambia. The researchers collected data from patient records in 2022 and 2023 to see how antibiotic use and prescribing habits changed after the programme was introduced.
They found that the overall use of antibiotics decreased from 81% of patients in 2022 to 71% in 2023. The use of ceftriaxone, the most commonly prescribed antibiotic, declined from 48% in 2022, to 38% in 2023. Prescribing antibiotics according to national guidelines (called Standard Treatment Guidelines) improved slightly, and the average number of antibiotics prescribed per patient was reduced from 1.38 to 1.21.
In conclusion, the AMS programme had an early positive impact on reducing unnecessary antibiotic use and improving adherence to treatment guidelines in the hospitals.
Details
Resource type: Article
Date: 13. March 2025
Publisher: Antibiotics
Author: Steward Mudenda, Kenneth Kapolowe, Uchizi Chirwa, Melvin Chanda, Raphael Chanda, Rodney Kalaba, Sombo Fwoloshi, Christabel Phiri, Mukuka Mwamba, Robert Kajaba Chirwa, Kotey Nikoi, Linda Musonda, Kaunda Yamba, Josepsh Yamweka Chizimu, Chitalu Chanda, Tamica Mubanga, Chisha Simutowe, John Kasanga, Mulope Mukanwa, Katongo Hope Mutengo, Philip Matthew, Fabian Maza Arnedo, Jyoti Joshi, Jonathan Mayito, Ruth Nakazwe, Maisa Kasanga, Duncan Chanda
Region: Africa
Sector: Humans
Share
Share this project on socials
Related resources

A Resource for Change: Harnessing gender insights to tackle antimicrobial resistance
ICARS, IDRC, HSRC, MORU, and Jive Media Africa

Scaling solutions and financing for antimicrobial resistance mitigation
ICARS and ReAct Africa

Mitigating antimicrobial resistance (AMR) using implementation research: a development funder’s approach
Mark P Khurana, Sabiha Essack, Ghada Zoubiane, Nandini Sreenivasan, Gloria Cristina Cordoba, Erica Westwood, Anders Dalsgaard, Robinson H Mdegela, Mirfin Mpundu, Rodrigo Scotini, Augustine B Matondo, Alexanda Mzula, Nina Chanishvili, Dimitri Gogebashvili, Maia Beruashvili, Marika Tsereteli, Talant Sooronbaev, Jesper Kjærgaard, Joakim Bloch, Elvira Isaeva, Geoffrey Mainda, Geoffrey Muuka, Ntombi B Mudenda, Fusya Y Goma, Duc-Huy Chu, Duncan Chanda, Uchizi Chirwa, Kaunda Yamba, Kenneth Kapolowe, Sombo Fwoloshi, Lawrence Mwenge, Robert Skov
Related projects
